THC

THC, or tetrahydrocannabinol, is one of the main cannabinoids naturally found in hemp and cannabis. It is one of the phytocannabinoids produced by the plant and is among the most studied compounds in the world of cannabis.

THC is synthesised in the trichomes, small microscopic structures found mainly on the flowers. Like many cannabinoids, it is not initially produced in its final form. In the living plant, it is first present as THCA, or tetrahydrocannabinolic acid, which is its natural precursor.

From THCA to THC

THC results from the transformation of THCA. This conversion occurs through a process known as decarboxylation, which takes place particularly under the effect of heat, time or certain processing methods.

Before this transformation, much of the plant’s THC potential is still in the form of THCA. This is why laboratories generally distinguish between these two molecules in their analyses.

A major cannabinoid in cannabis

THC is among the most abundant cannabinoids in many cannabis varieties. Its concentration varies according to genetics, growing conditions, light exposure, harvesting and the processing methods used.

Alongside CBD, CBG, CBN, CBC and other cannabinoids, it contributes to the plant’s complex chemical composition. Each variety therefore has its own cannabinoid profile.

Interaction with the endocannabinoid system

THC is studied for its interactions with the endocannabinoid system, a biological network found in humans and many animals. This system includes cannabinoid receptors, endocannabinoids naturally produced by the body and various enzymes involved in their functioning.

The interactions between plant cannabinoids and the endocannabinoid system are now an important area of scientific research.

Found in many products

THC can be found in flowers, resins, extracts and various cannabis-derived products. The concentrations observed vary considerably depending on the varieties, production methods and processing procedures used.

Laboratory analyses generally make it possible to measure THC and other cannabinoids in order to establish the composition profile of a given product.

At the heart of cannabis research

Because of its importance in the plant, THC is the subject of numerous studies focusing on its structure, biosynthesis, biological interactions and role in cannabis chemistry. It remains one of the best-known and most studied cannabinoids in the world.